Celox-A (All New Applicator Delivery System)

APPLICATOR DELIVERY SYSTEM FOR CELOX AGENT TO DEEP PENETRATING WOUNDS **

CELOX™ is a high performance chitosan-derived hemostatic designed to stop lethal bleeding fast. It is easy to use, extremely effective (clots blood in 30 seconds), and safe (is a CE Marked Class III Medical Device). CELOX comes in four different delivery systems, providing a commitment to aiding the caregiver in treating a variety of difficult and deep wounds. It also does not generate heat and will not burn the casualty or care giver. CELOX works independently of the body's normal clotting processes and has been proven to work in hypothermic conditions and in the presence of common anticoagulants such as Coumadin and Heparin.

The CELOX-A applicator and plunger delivery system makes it possible for the hemostatic agent to reach deep into small penetrating wounds, getting straight to the source of the bleeding.

When placed directly into a bleeding wound and subjected to pressure, the positively charged CELOX granules cross-link with negatively charged red blood cells, forming a sticky pseudo clot that blocks blood flow. This clot sticks well to moist tissue to plug the bleeding site. CELOX does not set off the normal clotting cascade. CELOX also does not set off a blood clotting response which would lead to clots being formed at a distance to the product.

CELOX is made of chitosan, a compound derived from shrimp shells. Chitosan has proven antimicrobial properties and is not a procoagulant. Chitosan is broken down and absorbed through normal metabolic pathways and has an extensive history of use in vascular closure and in human cardiac surgery.

CELOX has a three year history of use in emergency, military, and retail first aid with no reported incidents. An external review was commissioned on the safety of CELOX's ingredients in the body and concluded that CELOX was safe to use internally in surgery and that residual quantities presented no risk.

BENEFITS AND FEATURES

• Proven to control arterial bleeding within minutes
• Works in hypothermic conditions
• FDA cleared to work on anticoagulated blood
• No heat - no burning
• Sterile, waterproof packaging
• Easy to irrigate from wound
• Applied using basic first aid skills

• 6g (0.2oz) applicator/plunger

• EMS Personnel
• Military Medics
• Law Enforcement
• Wilderness Rescue